Anti-FRZB Antibody

Sourced from Antibodies.com, this primary antibody is a rabbit polyclonal reagent raised against FRZB (Frizzled-related protein 1), generated using a recombinant human FRZB protein as the immunogen and subsequently affinity-purified to specifically detect the endogenous total FRZB protein. The unconjugated antibody is supplied at a concentration of 1.0 mg/mL in a 50 µL volume, formulated in phosphate-buffered saline (pH 7.4) without Mg²⁺ and Ca²⁺, containing 150 mM sodium chloride, 0.02% sodium azide, and 50% glycerol as a cryoprotectant and preservative. Validated for Western Blot (WB) application, the reagent shows confirmed reactivity with human and mouse samples, making it suitable for cross-species studies of the Wnt signaling pathway. The polyclonal antibody is raised in rabbit, ensuring high affinity and consistent performance for routine immunoblotting workflows. Storage recommendations include shipping at 4°C with subsequent aliquoting and long-term storage at –20°C; users are advised to avoid repeated freeze/thaw cycles to maintain antibody integrity. The product is intended strictly for research use only and is not approved for diagnostic or therapeutic applications. FRZB, also known as sFRP-3, SFRP3, FIZ, Fritz, FRP, or FRZB1, is a secreted modulator of Wnt signaling with relevance to skeletal development, cancer biology, and extracellular matrix research. Affinity-purified and rigorously validated, this polyclonal reagent offers reliable detection of endogenous FRZB levels in standard Western Blot protocols and is dispatched from St. Louis, MO with a typical lead time of 6–9 business days.