Anti-Fructose-bisphosphate aldolase A Antibody

This rabbit polyclonal antibody from Antibodies.com specifically targets Fructose-bisphosphate aldolase A (ALDOA), a key glycolytic enzyme that catalyzes the reversible cleavage of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. ALDOA is most abundantly expressed in skeletal muscle, and altered expression is documented in cancer biology and metabolic disease research.

Supplied as a 100 µg aliquot in unconjugated form, the reagent is validated for Western blot and immunohistochemistry on human samples. Generated in rabbit, the polyclonal antibody binds several epitopes across the ALDOA protein, supporting detection in denaturing Western blot workflows and fixed-tissue immunohistochemistry. Storage at -20 °C in working aliquots helps preserve activity and limit freeze-thaw damage across repeated experiments.

Typical laboratory applications include Western blot loading control studies, characterization of glycolytic enzyme expression in tumor tissue sections, and immunohistochemistry profiling of muscle and cardiac biopsies. Investigators studying metabolic reprogramming, myogenesis, or oncology biomarker discovery rely on anti-ALDOA antibodies to track expression changes in response to experimental treatment or disease state.