Anti-Frizzled-10 Antibody

This rabbit polyclonal reagent from Antibodies.com specifically recognizes Frizzled-10, a seven-transmembrane G-protein-coupled receptor that mediates Wnt ligand binding and downstream β-catenin signaling. Validated for western blot and ELISA workflows, the antibody was raised in rabbit and is supplied as an unconjugated 100 µl aliquot, allowing flexible conjugation or direct detection in investigator-developed assays. The reagent cross-reacts with both human and mouse Frizzled-10, supporting translational studies that compare receptor expression across species. Frizzled-10 has attracted interest in oncology research, particularly in synovial sarcoma, gastric, and colorectal cancer investigations, where Wnt pathway activity drives tumor proliferation. Researchers commonly probe Frizzled-10 expression in cell lysates and tissue homogenates using western blot under reducing conditions, while ELISA can be adapted for quantitative receptor measurements. For optimal stability, store the vial at -20 °C in working aliquots to limit freeze-thaw cycles, and protect from light until first use.