Anti-FREQ Antibody

This polyclonal reagent from Antibodies.com targets FREQ, also known as FBXO18, an F-box family member with intrinsic DNA helicase activity linked to DNA damage response and homologous recombination repair. The unconjugated antibody is raised in rabbit and supplied at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol, as a 100 µl pack size. It has been validated for Western blot (WB) and immunohistochemistry (IHC) workflows, with reactivity confirmed in human, mouse, and rat samples. FREQ operates in nuclear DNA repair and genomic stability pathways, supporting studies of chromosome maintenance, cancer biology, and Fanconi anemia-associated repair mechanisms. The polyclonal format provides broader epitope coverage than monoclonal alternatives, allowing detection of multiple FREQ isoforms where they are expressed across tissue lysates and fixed sections.