Anti-FOXP3 Antibody

Raised in rabbit against the FOXP3 transcription factor, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl of antisera. FOXP3 (Forkhead Box P3) serves as the master regulator of regulatory T cell (Treg) development and immunosuppressive function, and expression of the approximately 47 kDa nuclear protein is widely used as a defining marker of the CD4⁺CD25⁺ Treg lineage in immunology, autoimmunity, and transplantation research. The antibody is validated for Western blot and ELISA workflows and has been confirmed to react with human, mouse, and rat samples, enabling studies of immune tolerance, tumor-infiltrating lymphocytes, and disorders such as IPEX syndrome that result from FOXP3 dysfunction. As an unconjugated polyclonal, the reagent provides flexibility for downstream labeling chemistries and the development of custom detection assays in both standard and exploratory formats.