Anti-FoxO1A Antibody

A rabbit polyclonal primary antibody from Antibodies.com targeting the FoxO1A transcription factor, a Forkhead box family member implicated in insulin signaling, gluconeogenesis regulation, oxidative stress response, and apoptotic control. This unconjugated reagent is supplied as a 100 µl liquid aliquot and is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA applications. Cross-reactivity has been confirmed with human, mouse, and rat samples, supporting broad use across metabolism, oncology, and neuroscience research programs.

The reagent pairs with standard anti-rabbit HRP, biotin, or fluorophore-conjugated secondary antibodies, allowing flexible detection strategies on Western blots, fixed tissue sections, or cultured cells. Investigators commonly deploy it to monitor FoxO1A expression, subcellular distribution, and Akt-driven phosphorylation at conserved regulatory residues, events that govern cytoplasmic retention versus nuclear accumulation of the transcription factor. Published uses include mapping hepatic glucose output, adipocyte differentiation, neuronal survival under oxidative challenge, and tumor suppressor pathway analyses.