Anti-FOXO1 Antibody

Raised in rabbit against the FOXO1 forkhead transcription factor, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied as a 50 µl vial and validated for Western blot and immunofluorescence workflows. The antibody binds endogenous FOXO1 in Human, Mouse, and Rat samples, supporting studies of AKT-dependent phosphorylation, nuclear-cytoplasmic shuttling following growth factor withdrawal, and downstream FoxO target gene regulation in metabolic, aging, and oncology contexts. Affinity purification of the rabbit antiserum yields a polyclonal reagent tolerant of minor sequence variation between orthologs and across post-translational modification states, while the unconjugated format lets researchers pair it with HRP, fluorophore, or biotinylated secondaries for chemiluminescent Western blot or fluorescence imaging detection. Intended for research use only, the vial supports cell culture and tissue lysate applications and can be combined with phospho-specific FOXO1 antibodies to dissect signaling dynamics in insulin signaling, oxidative stress, and apoptosis pathways.