Anti-FOS (phospho T232) Antibody

Raised in rabbit against a synthetic phosphopeptide spanning the Thr232 region of human FOS, this polyclonal IgG reagent from Antibodies.com selectively recognizes the c-Fos transcription factor only when phosphorylated at threonine 232. ERK/MAPK-driven modification of this residue drives nuclear localization and AP-1 transcriptional output, so the antibody is used to track MAPK pathway activity, immediate-early gene induction following growth factor or stress cues, and neuronal activation mapping where c-Fos serves as a canonical activity marker. The unconjugated IgG is supplied in a 100 µl single-use vial of liquid formulation in PBS pH 7.4 with 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, giving researchers flexibility to pair it with HRP, fluorescent, or biotin secondary reagents of their choice. Validated for western blot and immunofluorescence on human, mouse, and rat samples, it supports work in cultured cells and tissue cryosections. Aliquot on arrival, store at −20 °C, and limit freeze-thaw cycles to preserve phospho-epitope reactivity.