Anti-FMR1NB Antibody

The FMR1NB gene sits adjacent to FMR1 on the long arm of the X chromosome (Xq28), a region repeatedly examined in studies of X-linked intellectual disability and fragile X locus biology. This unconjugated rabbit polyclonal antibody from Antibodies.com is supplied as 50 µl of polyclonal IgG, raised against an FMR1NB immunogen and intended for research use only.

Validated applications include western blot (WB) for detection of the target band in lysates prepared from human, mouse, and rat samples, along with immunohistochemistry (IHC) on formalin-fixed tissue sections. Because the reagent is unconjugated, researchers can pair it with their preferred secondary reporter — HRP, fluorophore, or biotin conjugate — depending on the detection chemistry required.

FMR1NB displays a restricted tissue distribution, with documented expression in testis and lower-level transcripts reported in brain, which makes careful sample selection important for clean signal in WB and IHC experiments. Investigators focused on FMR1 locus regulation, fragile X premutation carriers, or candidate genes contributing to X-linked cognitive phenotypes use this reagent to confirm FMR1NB protein expression rather than relying solely on transcript data.

Each vial provides 50 µl of antibody preparation with IgG isotype, supporting reproducible western blot and immunohistochemistry workflows across human, mouse, and rat reactivity.