Anti-FMR1 Antibody

Recognizing the Fragile X Mental Retardation 1 protein (FMRP) in tissue and cell preparations, this unconjugated rabbit polyclonal reagent from Antibodies.com supports neuroscience and disease research targeting the gene responsible for Fragile X syndrome. FMRP functions as an RNA-binding translational regulator, with strongest expression in neurons where it governs dendritic mRNA localization and synaptic plasticity; CGG-repeat expansions or loss-of-function mutations in FMR1 also underlie FXTAS and FXPOI. Supplied at 1 mg/ml in 100 µl aliquots buffered in PBS with 0.1% sodium azide and 50% glycerol, the antibody is validated for Western blot, immunohistochemistry, and immunofluorescence on human, mouse, and rat specimens.