Anti-FMO3 Antibody

Primary antibody targeting Flavin-containing monooxygenase 3 (FMO3), a microsomal enzyme expressed predominantly in adult liver that catalyzes the NADPH-dependent oxidation of nitrogen-, sulfur-, and phosphorus-containing xenobiotics, including therapeutic drugs and dietary amines. Loss-of-function variants in FMO3 underlie the inherited metabolic disorder trimethylaminuria, and inter-individual variation in hepatic FMO3 activity is a recognized contributor to differences in drug clearance and toxicology.

This polyclonal reagent from Antibodies.com is raised in rabbit (IgG isotype), supplied unconjugated in a 200 µL vial, and validated for detection of human, mouse, and rat samples. Recommended applications include Western blot for the approximately 55-60 kDa FMO3 protein and immunofluorescence for subcellular localization studies. The unconjugated format allows flexible pairing with secondary reagents for downstream assays.

For storage, refrigerate short-term and aliquot before freezing if held longer; avoid repeated freeze-thaw cycles. For research use only.