Anti-FMNL1 Antibody

The polyclonal reagent targets FMNL1 (Formin-like protein 1), a member of the formin family of actin-nucleating proteins expressed predominantly in hematopoietic lineages including lymphocytes, macrophages, and neutrophils. FMNL1 participates in actin cytoskeleton remodeling, phagocytic cup formation, cell adhesion, and migration, so it is frequently investigated in studies of innate immune signaling, leukocyte motility, and hematological malignancies such as acute myeloid leukemia and select lymphomas.

Supplied by Antibodies.com as 100 µL of unconjugated rabbit antiserum, this primary antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human tissue and cell samples. Researchers apply it to confirm FMNL1 expression in cultured cell lines, characterize cytoskeletal reorganization following immune stimulation, and map protein distribution in fixed tissue sections where formin-driven actin dynamics are of interest.

The polyclonal format recognizes multiple epitopes across the FMNL1 sequence, which is advantageous when probing conformational variants or partially degraded targets in lysate preparations. For routine handling, aliquot upon first use and store refrigerated; repeated freeze-thaw cycles should be avoided to preserve binding activity. Each vial is intended as a single-use research reagent for laboratory investigation.