Anti-FLNA Antibody

This unconjugated polyclonal reagent from Antibodies.com targets Filamin A (FLNA), a large actin-crosslinking protein that organizes the cortical cytoskeleton, anchors transmembrane receptors at the cell periphery, and participates in mechanotransduction signaling cascades. Produced in rabbit and supplied as a 100 µl vial, the antibody supports reproducible detection in Western blot and immunohistochemistry workflows against human and mouse samples.

Filamin A scaffolds interactions with integrins, Rho-family GTPases, and a range of cytoplasmic partners, making this reagent useful for investigations into cytoskeletal remodeling, cell migration, focal adhesion biology, and the X-linked developmental disorders associated with FLNA mutations. The unconjugated format gives laboratories flexibility to couple the antibody to their preferred fluorophore or enzyme label when developing custom immunostaining protocols, immunoprecipitation assays, or paraffin-section chromogenic stains. The polyclonal clonality broadens the range of FLNA epitopes recognized, which is helpful when probing truncated isoforms or post-translationally modified variants.

Aliquot upon receipt and store at -20°C to preserve binding activity. Protect from light and limit repeated freeze-thaw cycles to maintain performance across the product's shelf life.