Anti-FLCN Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent targets FLCN (Folliculin), the protein linked to Birt-Hogg-Dubé syndrome and fibrofolliculoma skin lesions. It is supplied at 1.0 mg/mL in a 50 µl volume, formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol, and was affinity-purified against a recombinant human FLCN immunogen. The antibody is unconjugated and of the IgG isotype, giving researchers flexibility to pair it with their preferred secondary labels. Validated applications include Western blotting (suggested dilution 1:500 – 1:2000) and immunohistochemistry, with immunofluorescence working ranges of 1:50 – 1:100 also reported, and the reagent detects endogenous total FLCN in human, mouse and rat samples. The product is dispatched from Cambridge, UK, on blue or wet ice; upon receipt, users are advised to aliquot and store at –20 °C and to avoid repeated freeze/thaw cycles to preserve binding activity. Suitable for studies of BHD syndrome biology, mTORC1/AMPK signalling and comparative folliculin expression, this polyclonal offers a versatile option for both denaturing and native detection workflows.