Anti-FKBPL Antibody

Raised in rabbit against recombinant human FKBPL immunogen and affinity-purified by epitope-specific chromatography, this polyclonal IgG reagent from Antibodies.com is supplied as 50 µl of unconjugated liquid in a single-use vial. Validated for western blot detection of endogenous FKBPL across human, mouse, and rat samples, the antibody recognizes the approximately 38 kDa WISP39/DIR1 protein (UniProt Q9UIM3), a divergent member of the FKBP immunophilin family linked to p21/CIP1 stabilization, modulation of androgen receptor signaling, and regulation of angiogenesis and the DNA damage response. The reagent is buffered for direct application to immunoblotting membranes after standard SDS-PAGE separation and transfer. Published studies have used this class of antibody to probe FKBPL expression and subcellular localization in breast and prostate cancer cell models, supporting investigation of tumor proliferation, cell cycle checkpoint control, and induced radioresistance. For research use only.