Anti-FKBP8 Antibody

This polyclonal antibody from Antibodies.com targets FKBP8, a mitochondrial immunophilin that regulates apoptosis and mitophagy through interactions with Bcl-2 family members and mTOR signaling. Raised in rabbit, it recognizes the endogenous FKBP8 protein in human, mouse, and rat samples, supporting translational research into neurodegenerative disease pathways, apoptosis control, and mitochondrial quality control.

The reagent is supplied as 100 µl of liquid at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, providing freezer-stable handling for routine laboratory use. Recommended storage at -20 °C with aliquoting to limit freeze-thaw cycles preserves binding activity across multiple experiments. The unconjugated Ig fraction allows flexible pairing with secondary antibodies or custom labeling workflows. For western blot, the antibody detects the expected band in lysates from cell lines and primary tissue, while immunohistochemistry and immunofluorescence applications reveal the characteristic mitochondrial and endoplasmic reticulum-associated distribution of FKBP8 in fixed cells and tissue sections.