Anti-FKBP4 Antibody

This primary antibody from Antibodies.com is a rabbit polyclonal reagent that specifically recognizes FKBP4, the 52 kDa FK506-binding immunophilin commonly referenced in the literature as FKBP52. The antibody is supplied as 100 µl of a 1 mg/ml stock in PBS with 0.1% Sodium Azide and 50% Glycerol, and is provided unconjugated so it can be integrated into standard chromogenic, fluorescent, or chemiluminescent detection workflows without modification.

Validated applications include Western blot, immunohistochemistry, and immunofluorescence, covering the principal readouts used in studies of steroid receptor chaperone biology. FKBP4 acts as a co-chaperone that modulates the activity of glucocorticoid, androgen, progesterone, and estrogen receptors, and it also contributes to microtubule stabilization and mitotic progression. Researchers working on hormone-driven cancer models, glucocorticoid signaling, or cell cycle regulation commonly use anti-FKBP4 antibodies to track co-chaperone recruitment to receptor complexes in both lysate and tissue-based assays.

Reactivity has been confirmed against human, mouse, and rat samples, supporting cross-species experimental design in cell line panels, xenograft tissue, and primary animal samples. For storage, aliquot the antibody upon receipt and freeze at -20°C to preserve activity across multiple freeze-thaw cycles, keeping working stocks refrigerated at 4°C for short-term use and protecting the vial from light.