Anti-FKBP2 Antibody

This rabbit polyclonal antibody targets FKBP2, a 14 kDa immunophilin of the FK506-binding protein family that functions as a peptidyl-prolyl cis-trans isomerase (PPIase) and serves as the intracellular receptor for the immunosuppressive ligands FK506 and rapamycin. The antigen localizes to the endoplasmic reticulum and secretory pathway, where it supports protein folding, vesicular trafficking, and modulation of intracellular calcium-release channels, and has been investigated in T-cell activation, mTOR signaling, and cellular stress pathways.

Supplied as a 50 µL vial of unconjugated IgG, the reagent is applicable to Western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat samples. Laboratories commonly deploy it to map FKBP2 distribution in tissue sections, monitor expression shifts following genetic or pharmacological perturbation of the FKBP family, and explore roles within rapamycin-sensitive signaling networks. Recommended handling includes refrigeration for routine use and aliquoting to limit freeze-thaw cycling.

From Antibodies.com, this polyclonal reagent is intended for research use only and integrates cleanly into standard chromogenic IHC and fluorescence imaging pipelines alongside common anti-rabbit secondary antibodies.