Anti-FKBP1A Antibody

Raised in rabbit and supplied at 100 µl, this polyclonal reagent from Antibodies.com targets FKBP1A (also called FKBP12), a ~12 kDa immunophilin that binds the immunosuppressants FK506 and rapamycin and modulates intracellular calcium release through ryanodine and IP3 receptor channels. The antibody is validated for Western blot (WB) and immunohistochemistry (IHC) on human, mouse, and rat samples, supporting work in TGF-beta signaling, mTOR pathway regulation, and T-cell activation biology. The unconjugated format lets researchers pair the reagent with their choice of secondary labels for fluorescence, chromogenic, or chemiluminescent detection. To preserve activity, aliquot on receipt to limit freeze-thaw cycles and protect from light when fluorescent secondaries are used downstream. The polyclonal design enables recognition of multiple epitopes on the target, increasing robustness across varied sample preparations.