Anti-FIGNL1 Antibody

This rabbit polyclonal primary antibody specifically targets Fidgetin-like 1 (FIGNL1), an AAA+ ATPase implicated in DNA double-strand break repair and homologous recombination. Produced by Antibodies.com, the reagent is supplied as 100 µl of unconjugated IgG at 1 mg/ml in phosphate buffered saline with 15 mM sodium azide, at approximately pH 7.2.

The antibody was raised in rabbit and is validated for Western blot detection of endogenous FIGNL1 protein in human, mouse, and rat samples, supporting comparative expression studies across these species. Its polyclonal format increases the likelihood of recognizing distinct epitopes on FIGNL1, which is useful when probing low-abundance targets in cell lysate or tissue extracts.

FIGNL1 functions in resection and repair of DNA damage, and researchers have used antibodies of this type to investigate its recruitment to damage sites. The unconjugated format allows the antibody to be paired with a secondary reporter of choice for chemiluminescent Western blot workflows. For handling, aliquot the antibody to limit repeated freeze-thaw cycles and refrigerate when in use.