Anti-Fibulin-2 (E279) Antibody

Raised in rabbit, this polyclonal reagent from Antibodies.com targets Fibulin-2 (FBLN2), a calcium-binding extracellular matrix glycoprotein that organizes basement membranes and elastic fiber networks across connective tissue, vascular walls, and dermal layers. The antibody was generated against an epitope mapped to the E279 region and is supplied as a 100 µl vial at approximately 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at pH 7.2. It is unconjugated, allowing flexible pairing with user-selected secondary detection systems.

Validated methods include Western blot analysis of Fibulin-2 in cell and tissue lysates, and immunohistochemistry localization of the antigen in formalin-fixed tissue sections. Reactivity is reported against human samples, supporting investigations of matrix remodeling, vascular biology, fibrotic disease, and tumor-stroma interactions in cancer research.

Working dilutions should be titrated empirically for each application. The product is intended for research use only and is not approved for diagnostic or therapeutic use. Storage in a refrigerated environment is recommended, with aliquoting advised to limit freeze-thaw cycles and preserve antibody activity across the shelf life of the reagent.