Anti-FHL1 Antibody

The Four and a Half LIM Domains protein 1 (FHL1) is a multifunctional scaffolding factor best known for its roles in striated muscle and as a transcriptional co-regulator. This rabbit polyclonal reagent from Antibodies.com was raised against FHL1 and is supplied as 100 µl of unconjugated antiserum for Western blot (WB) and immunohistochemistry (IHC) workflows on human samples.

As a polyclonal preparation, the antibody recognizes multiple epitopes across the target, which can be useful when probing full-length FHL1 alongside its shorter isoforms such as FHL1B and FHL1C that arise from alternative splicing. The unconjugated format leaves the choice of label and detection chemistry to the researcher, supporting chromogenic IHC on fixed tissue sections as well as standard immunoblotting of cell and tissue lysates.

Because FHL1 expression and localization shift in the context of X-linked myopathies and several carcinomas, the antibody is positioned for studies of muscle biology, cardiac development, and tumor-suppressor pathways. The reagent is shipped refrigerated; aliquot upon arrival and avoid repeated freeze-thaw cycles of the antibody solution.