Anti-FHIT Antibody

Manufactured by Antibodies.com, this rabbit polyclonal reagent targets the fragile histidine triad (FHIT) tumor suppressor and is supplied as a 50 µl aliquot at a working concentration of 1.0 mg/mL. The antibody was raised against a synthesized peptide derived from human FHIT and was affinity-purified from rabbit antiserum by affinity-chromatography using the epitope-specific immunogen, yielding an unconjugated, ready-to-use Rabbit IgG preparation in phosphate buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. It is validated for western blotting (WB), immunohistochemical staining of formalin-fixed paraffin-embedded sections (IHC) and immunocytochemistry/immunofluorescence imaging (ICC/IF), and it specifically detects endogenous levels of total FHIT protein in human samples. Researchers should note the shipping and storage conditions: the product is shipped at 4 °C and, upon delivery, should be aliquoted and stored at −20 °C, with repeated freeze/thaw cycles avoided to preserve antibody performance. As a research-use-only polyclonal reagent with documented reactivity toward human FHIT, this offering is well suited to laboratories investigating the role of the FHIT tumor suppressor in cancer biology, signal transduction, and related cell regulatory pathways.