Anti-FHIT Antibody

FHIT (Fragile Histidine Triad Diadenosine Triphosphate Hydrolase) is a well-characterized tumor suppressor protein encoded at the fragile FRA3B locus on chromosome 3p14.2, and loss of FHIT expression is widely documented in lung, breast, head and neck, cervical, and gastrointestinal cancers. This rabbit polyclonal anti-FHIT antibody from Antibodies.com is raised against the human FHIT protein and supplied as an unconjugated reagent in a 100 µl volume, ready for use in western blot, immunohistochemistry, and immunofluorescence workflows. Researchers commonly deploy it to confirm endogenous FHIT levels in cell lysates, localize FHIT within fixed tissue sections, and examine subcellular distribution in cultured human cell lines. The antibody reacts with human FHIT and is offered as a polyclonal reagent, which provides broader epitope coverage useful when probing for truncated or downregulated variants of the protein frequently observed in tumor samples. It is shipped as a liquid polyclonal IgG preparation intended for research use only, with no additional label or conjugate, allowing flexibility for downstream fluorescent or enzymatic secondary antibody detection.