Anti-FH Antibody

Mouse monoclonal antibody raised against fumarate hydratase (FH), a mitochondrial Krebs cycle enzyme and recognized tumor suppressor that catalyzes the reversible hydration of fumarate to malate. This unconjugated primary reagent is supplied as 100 µl of purified antibody and is validated for Western blot and immunofluorescence workflows on human, mouse, and rat samples. Generated in mouse hosts as a monoclonal product, the antibody provides consistent recognition of the conserved FH target for laboratories investigating TCA-cycle metabolism, mitochondrial dysfunction, and fumarate-driven oncogenesis, including hereditary leiomyomatosis and renal cell cancer (HLRCC) research. Provided by Antibodies.com, the antibody is unconjugated for flexible secondary-labeling strategies and supports immunoblotting of endogenous fumarase expression as well as cell-based imaging of subcellular localization in normal and tumor tissue contexts.