Anti-FGL1 Antibody

FGL1 (Fibrinogen-like protein 1) is a hepatocyte-derived secreted glycoprotein that acts as a major inhibitory ligand for the LAG-3 immune checkpoint, and it has become an active focus of cancer immunology research. This unconjugated rabbit polyclonal IgG primary antibody, supplied by Antibodies.com as a 100 ul vial, was raised against FGL1 and validated for western blot detection in human, mouse, and rat samples. Investigators working on hepatocellular carcinoma, metabolic liver disease, and the FGL1-LAG-3 axis in tumor immune evasion rely on polyclonal reagents of this type to monitor endogenous expression across cell lysates and tissue homogenates. Aliquot the antibody upon receipt and store at -20 °C in single-use portions, avoiding repeated freeze-thaw cycles that can compromise immunoglobulin binding. The polyclonal format increases the chance of recognising multiple FGL1 epitopes, which is useful when probing truncated isoforms or when signal from a single monoclonal clone is weak.