Anti-FGFR2 Antibody

FGFR2 (Fibroblast Growth Factor Receptor 2) is a receptor tyrosine kinase central to cell proliferation, differentiation, and embryonic development. This rabbit polyclonal antibody from Antibodies.com targets FGFR2 and is supplied as an unconjugated IgG in a 200µl volume, ready for direct labeling or use in standard detection workflows. Validated applications include Western blot, immunohistochemistry, immunofluorescence, and flow cytometry, with demonstrated reactivity against human, mouse, rat, and monkey samples.

Researchers rely on this reagent for investigating FGFR2-driven signaling in oncology — particularly gastric, breast, and endometrial cancers where FGFR2 amplification or mutation is implicated — as well as in studies of skeletal dysplasias such as Apert, Crouzon, and Pfeiffer syndromes, where activating FGFR2 mutations alter craniofacial and limb development. The polyclonal format provides recognition of multiple epitopes across the receptor, which can be advantageous when probing isoforms or mutant variants. For long-term storage, the antibody should be aliquoted and kept at -20°C to preserve activity across multiple freeze-thaw cycles; for shorter experiments, refrigerated conditions are appropriate.

The unconjugated format gives laboratories flexibility to pair the antibody with their own secondary reagents, fluorophores, or enzyme systems. The reagent is also suitable for immunohistochemistry, flow cytometry, and immunofluorescence, and is appropriate for research use only in laboratory investigations of FGFR2 biology, signaling pathway mapping, and translational oncology programs.