Anti-FGFR1 (phospho Y766) Antibody

Raised in rabbit, this polyclonal antibody from Antibodies.com targets the phosphorylated form of Fibroblast Growth Factor Receptor 1 at tyrosine 766 (FGFR1 phospho Y766), a residue associated with receptor activation and downstream signaling through PLCγ and other pathways involved in cell proliferation, differentiation, and migration.

Supplied as 50 µl of unconjugated IgG, the reagent is validated for Western blot detection in human samples, supporting studies of FGFR1 autophosphorylation, kinase signaling cascades, and receptor regulation in cancer research and developmental biology contexts.

The antibody enables detection of the activated receptor state rather than total FGFR1 expression, allowing researchers to distinguish basal signaling from ligand-induced or mutation-driven activation. This specificity supports investigations into FGFR1 amplification, gene fusions, and pathogenic variants linked to multiple solid tumors and hematologic malignancies.

For research use only. Working dilutions should be optimized for the specific lysate preparation and detection system. Store at -20 °C in appropriate aliquots to preserve activity and avoid repeated freeze-thaw cycles.