Anti-FGFR1 (phospho Y766) Antibody

This polyclonal primary antibody from Antibodies.com is raised in rabbits and supplied as an unconjugated IgG preparation in a 200 µl vial, validated for western blot detection of the FGFR1 receptor tyrosine kinase in human samples. The reagent specifically recognises the phosphorylated tyrosine 766 (Y766) epitope within the intracellular kinase domain of FGFR1, enabling researchers to monitor ligand-induced autophosphorylation events that drive downstream MAPK and PLCγ signalling cascades. Typical applications include studies of FGF-stimulated signalling in cultured cell models and primary tissue lysates, supporting research into receptor activation dynamics in developmental biology and in cancers where aberrant FGFR1 activity contributes to proliferation and survival. The phosphorylation-site specificity allows users to distinguish ligand-activated receptor pools from total FGFR1 expression in parallel western blot experiments. For storage, keep the antibody frozen at -20 °C and divide into smaller aliquots when first opened to limit freeze-thaw cycles and preserve antigen-binding activity across multiple experiments.