Anti-FGFR1 Oncogene Partner Antibody

FGFR1OP is a centrosomal scaffolding protein most often studied in the context of the 8p11 myeloproliferative syndrome, where chromosomal translocations fuse it to the FGFR1 tyrosine kinase. To probe its expression and localisation, Antibodies.com offers a rabbit polyclonal primary antibody raised against the FGFR1 Oncogene Partner protein, supplied as an unconjugated 50 µl aliquot. The reagent is validated for Western blot and immunohistochemistry on formalin-fixed paraffin-embedded tissue, and it cross-reacts with the human, mouse, and rat orthologues, supporting comparative work across established model systems. Researchers apply it to map FOP at the centrosome, to confirm FGFR1OP-FGFR1 fusion protein expression, and to investigate centrosome maturation, microtubule anchoring, and the cytogenetic abnormalities associated with 8p11-rearrangement myeloid neoplasms. The polyclonal format raises the likelihood of recognising multiple epitopes, which helps when probing fixed sections or working with fusion constructs that retain only portions of the native protein.