Anti-FGFR1 Antibody

For mouse tissue studies, this unconjugated rabbit polyclonal IgG from Antibodies.com targets endogenous Fibroblast Growth Factor Receptor 1 (FGFR1), a transmembrane receptor tyrosine kinase involved in cell proliferation, migration, and differentiation. Supplied as 100 µL, the primary antibody is validated for immunohistochemistry and supports receptor-localization studies in fixed tissue sections. Its unconjugated format allows researchers to select an appropriate secondary antibody and detection system for their established staining workflow.

Typical applications include comparing FGFR1 distribution in normal and diseased tissue, examining receptor expression in genetically modified mouse models, and mapping developmental patterns in organs such as the lung. The reagent is useful in oncology research, where FGFR1 amplification, mutation, and pathway activity are investigated in breast, lung, and brain tumors, as well as in angiogenesis, neural stem-cell, and tumor-microenvironment studies. Because the antibody is directed against total FGFR1, it can help establish spatial expression patterns to complement functional or molecular assays rather than determine a specific FGFR1 mutation. Aliquot on arrival and avoid repeated freeze-thaw cycles to maintain antibody performance across staining runs. For research use only; not intended for diagnostic or therapeutic applications.