Anti-FGF23 Antibody

From Antibodies.com, this Rabbit polyclonal antibody targets fibroblast growth factor 23 (FGF23), the endocrine hormone implicated in phosphate and vitamin D metabolism, and is supplied as a 50 µl liquid aliquot at 1 mg/ml in PBS containing 0.1% sodium azide and 50% glycerol as a cryoprotectant. The unconjugated IgG reagent is raised in rabbit, is of polyclonal clonality, and is validated for Western blot and Immunohistochemistry on human samples, where it is expected to detect endogenous levels of the target phosphatonin. For short-term handling the vial should be kept refrigerated, with long-term storage at -20 °C in small aliquots to limit damage from repeated freeze-thaw cycles; the sodium azide preservative inhibits microbial growth in the working solution. Researchers studying FGF23 signaling in renal phosphate handling, tumor-induced osteomalacia, autosomal dominant hypophosphatemic rickets, or chronic kidney disease–mineral and bone disorder will find this reagent a convenient primary antibody choice for both WB band detection around the reported 27 kDa FGF23 molecular weight and IHC localization studies.