Anti-FGF14 Antibody

This polyclonal reagent from Antibodies.com targets fibroblast growth factor 14 (FGF14), an intracellular member of the FGF family that is expressed predominantly in the central nervous system, with strong localization in the cerebellum and hippocampus. FGF14 has been linked to spinocerebellar ataxia type 27 (SCA27) and to the regulation of voltage-gated sodium channels in neurons, making it a relevant marker in neurobiology and neurodegeneration research.

Raised in rabbit and supplied unconjugated at 100 µl, this primary antibody is validated for Western blot and immunofluorescence workflows, and it has been confirmed to react with human, mouse, and rat samples. Researchers commonly apply it to characterize FGF14 expression in brain tissue lysates, to probe the subcellular distribution of the protein in neuronal cultures, and to investigate its role in ion channel modulation and ataxia-related pathways.

Intended for research use only, the antibody supports immunoblotting of cell and tissue extracts as well as fluorescence imaging of fixed sections, enabling studies of cerebellar function, neuronal signaling, and disease-associated changes in FGF14 expression across multiple model systems.