Anti-FGB Antibody

Fibrinogen beta chain (FGB) is one of three polypeptide subunits that make up the circulating fibrinogen hexamer, the soluble precursor of fibrin that is cleaved by thrombin during clot formation. Antibodies.com offers a rabbit polyclonal antibody raised against FGB, supplied as 100 µl of unconjugated antiserum suitable for western blot and immunohistochemistry workflows on human and mouse samples. The polyclonal format delivers recognition of multiple epitopes across the FGB protein, which is helpful when studying fibrinogen biosynthesis in hepatocytes, plasma coagulation studies, or tissue-level expression of fibrinogen in liver, vasculature, and tumor microenvironments. The reagent is provided as a liquid in a single vial and can be paired with HRP- or fluorophore-conjugated secondary antibodies depending on the detection chemistry of the assay. Researchers investigating thrombin-mediated fibrin formation, fibrin(ogen) deposition in disease models, or hepatic acute-phase responses can use this reagent in standard western blot and IHC protocols.