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Anti-FEN1 Antibody
  • Anti-FEN1 Antibody
Antibodies.com

Anti-FEN1 Antibody

Price on request

SKUPriceQuantity
A38417-100

Price on request

Description

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The FEN1 protein (Flap Endonuclease 1) is a ~42 kDa structure-specific endonuclease central to maintaining genomic integrity through its dual roles in Okazaki fragment maturation during DNA replication and long-patch base excision repair. This unconjugated rabbit polyclonal reagent from Antibodies.com detects endogenous human, mouse, and rat FEN1 in western blot and immunohistochemistry workflows, with the 100 µl vial supplying sufficient volume for multiple membrane probing cycles and serial tissue section staining.

  • Target: FEN1 (Flap Endonuclease 1), a structure-specific nuclease essential for DNA replication and repair
  • Host species: Rabbit
  • Clonality: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Human, Mouse, Rat
  • Applications: Western blot (WB), Immunohistochemistry (IHC)
  • Format: 100 µl vial

FEN1 removes 5' overhanging flap structures generated during lagging-strand synthesis and also participates in resolving stalled replication forks. Dysregulated FEN1 expression has been documented across multiple tumor types, positioning the protein as a relevant marker in cancer biology and DNA damage response investigations.

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