Anti-FDFT1 Antibody

Squalene synthase sits at the first committed branch of sterol biosynthesis, and this rabbit polyclonal Anti-FDFT1 Antibody from Antibodies.com gives researchers an unconjugated reagent that recognizes human, mouse, and rat forms of farnesyl-diphosphate farnesyltransferase 1. The endoplasmic reticulum membrane enzyme couples two farnesyl diphosphate molecules head-to-head to produce squalene, the precursor of cholesterol, ubiquinone, and dolichol.

Validated for Western blot and immunofluorescence, the antibody is dispensed in a 100 µl vial as a polyclonal preparation. Labs investigating hepatic lipid metabolism, statin response pathways, and altered cholesterol flux in tumor cells commonly load whole-cell lysates for immunoblotting and fix cultured cells for IF imaging. The unconjugated format supports downstream labeling with HRP, fluorophore, or biotin conjugates selected by the user. Aliquot upon first thaw, avoid repeated freeze-thaw cycles, and store refrigerated to preserve reactivity across multiple experiments.