Anti-FCGR2B Antibody

FCGR2B is a low-affinity immunoglobulin G Fc region receptor II-b that acts as an inhibitory receptor on B lymphocytes and other immune cells, modulating antibody-mediated effector responses and maintaining peripheral tolerance. This rabbit polyclonal reagent from Antibodies.com targets the human FCGR2B protein and is supplied as an unconjugated preparation in a 100 µl vial. It is validated for western blot (WB) and immunohistochemistry (IHC) workflows on human samples, supporting studies of B cell biology, autoimmune disease mechanisms such as systemic lupus erythematosus, and Fc receptor signaling pathways that govern antibody-driven immune regulation. The polyclonal format provides recognition of multiple epitopes across the FCGR2B extracellular region, which can be particularly useful when probing native protein in transfected cell lines and primary lymphoid tissue.