Anti-FBXL12 Antibody

This Rabbit polyclonal antibody from Antibodies.com is raised against FBXL12 (F-box and leucine-rich repeat protein 12), a substrate-recognition subunit of the SCF E3 ubiquitin ligase complex that directs target proteins toward ubiquitination and subsequent proteasomal turnover. The reagent is supplied as 100 µl of unconjugated antisera in a vial, validated for western blot and immunohistochemistry across Human and Mouse samples.

FBXL12 contributes to substrate selectivity within the Cullin-1–RING ligase machinery and has been studied in the context of p53 regulation and other cellular control pathways. Researchers use this Anti-FBXL12 Antibody to detect endogenous expression, map SCF complex assembly, or monitor changes in FBXL12 abundance across disease models and primary tissues.

For handling, store at -20 °C in small aliquots to limit freeze-thaw cycles; the polyclonal format provides multi-epitope recognition, supporting work on FBXL12 under varying post-translational or conformational states.