Anti-FAT4 Antibody

This rabbit polyclonal antibody from Antibodies.com specifically recognizes FAT4 (FAT Atypical Cadherin 4), a large atypical protocadherin implicated in planar cell polarity, Hippo pathway signaling, and tumor suppression. The unconjugated IgG reagent is supplied as 100 µg in a liquid format validated for Western blot and immunocytochemistry workflows on human samples. For optimal stability, store at -20 °C in small working aliquots and avoid repeated freeze-thaw cycles. Researchers commonly apply this reagent to investigate FAT4 mutations linked to Hennekam lymphangiectasia–lymphedema syndrome, meningioma, gastric cancer, and colorectal carcinoma, where loss of FAT4 function contributes to dysregulated YAP/TAZ activity and aberrant cell migration.