Anti-FAS Antibody

FAS (also known as CD95, APO-1, or TNFRSF6) is a member of the tumor necrosis factor receptor superfamily that triggers the extrinsic apoptotic cascade when engaged by FAS ligand. This Rabbit polyclonal reagent from Antibodies.com was raised against human FAS and is supplied as an unconjugated, 100 µl liquid aliquot validated for western blot and immunohistochemistry applications on human samples.

The antibody supports detection of the FAS receptor in cell lysates and tissue sections, enabling studies of programmed cell death, immune tolerance, T-cell activation, and tumor immune evasion. Because polyclonal preparations engage multiple epitopes, they can offer broader recognition of FAS isoforms and cleaved receptor fragments compared with monoclonal reagents, useful when probing tissues where alternative splicing or receptor processing is suspected.

For western blot, pair with HRP-conjugated secondary antibodies and chemiluminescent detection. For immunohistochemistry, citrate buffer antigen retrieval at pH 6.0 on formalin-fixed, paraffin-embedded sections is commonly used. To preserve activity, refrigerate the vial and avoid repeated freeze-thaw cycles by aliquoting on first thaw. Research use only.