Anti-FANCC Antibody

FANCC is a member of the Fanconi anemia complementation group that participates in the FA core complex, the multi-subunit machinery responsible for repairing DNA interstrand cross-links and sustaining chromosomal stability during replication. This rabbit polyclonal antibody from Antibodies.com binds endogenous FANCC in human and mouse samples, supplied as a 100 µl unconjugated aliquot ready for western blot, immunohistochemistry, and immunofluorescence detection.

Investigators working on Fanconi anemia subtype C, hereditary bone marrow failure, or general DNA damage response signaling can apply the reagent to whole-cell lysates, fixed tissue sections, and cultured cells. The polyclonal format increases the probability of recognizing multiple epitopes on the target protein, which can be useful when probing truncated variants or low-abundance samples.

For handling, store at -20 °C in working aliquots to minimize freeze-thaw cycles, and pair with an appropriate secondary reagent for the chosen detection platform.