Anti-FAM120A Antibody [Assigned #A3389]

This mouse monoclonal antibody from Antibodies.com targets FAM120A, a constitutive transport element-binding protein with documented roles in oxidative-stress signaling and stress-granule dynamics. Clone A3389 was generated against the human antigen and is supplied as an unconjugated IgG in a 100 µL vial, ready for incorporation into western blot, immunohistochemistry, and immunofluorescence workflows.

FAM120A resides predominantly in the cytoplasm under basal conditions and redistributes to cytoplasmic stress granules when cells are challenged with oxidative insults such as sodium arsenite, providing a useful readout for translational silencing assays by immunofluorescence. Researchers investigating RNA-binding protein complexes, the CCR4-NOT deadenylase interactome, or constitutive mRNA transport pathways commonly use this reagent, often alongside IHC profiling of stress-responsive tissues and tumor specimens.

The unconjugated format gives flexibility in secondary detection, supporting HRP-based chromogenic staining of paraffin sections, chemiluminescent immunoblotting of whole-cell lysates, and multi-color fluorescence imaging for subcellular localization studies. Aliquots are intended for research use only and should be handled with the standard precautions applied to antibody reagents, including brief centrifugation before use to recover the full liquid volume from the vial.