Anti-FAK (I401) Antibody

Raised in rabbit and supplied at 1 mg/ml in phosphate buffered saline with 15 mM sodium azide, this unconjugated polyclonal antibody from Antibodies.com selectively binds Focal Adhesion Kinase (PTK2) across human, mouse, and rat samples.

Researchers apply the 50 µl vial in western blot workflows to resolve the native kinase band in cell lysates, and in immunohistochemistry to localize the protein to focal adhesions and membrane-associated structures in fixed tissue sections.

The reagent supports studies of integrin signaling, cytoskeletal remodeling, cell migration, and tumor invasion, where phosphorylation of the FAK autophosphorylation site is commonly tracked alongside total kinase expression.

Refrigerated storage preserves activity between uses, while the azide-containing buffer limits microbial contamination during routine benchtop handling. Compatible with standard HRP- and fluorophore-conjugated secondary reagents, the unconjugated format also permits custom conjugation for multiplexed imaging or proximity ligation assays.