Anti-FAK Antibody

Focal Adhesion Kinase (FAK), also known as PTK2, is a non-receptor cytoplasmic tyrosine kinase that localizes to focal adhesions and plays a central role in integrin-mediated signal transduction. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against FAK and cross-reacts with human, mouse, and rat samples, supporting reproducible detection across basic and translational research workflows.

Validated for western blot, immunohistochemistry, immunofluorescence, and ELISA applications, the antibody targets the ~125 kDa kinase and is supplied as a 100 µl liquid aliquot. Each lot is affinity-purified from rabbit serum and tested across the listed species to confirm consistent specificity. Researchers studying cell migration, cytoskeletal remodeling, tumor invasion, and integrin signaling pathways use this reagent to probe FAK phosphorylation status, expression levels, and subcellular localization in cultured cells, tissue sections, and whole-cell lysates.

For short-term storage keep the vial refrigerated at 4°C; for extended use, aliquot and freeze at -20°C to preserve binding activity through multiple freeze-thaw cycles. The single-use vial format suits individual bench projects, and the polyclonal host offers broader epitope coverage than monoclonal alternatives when surveying FAK isoforms or modified variants.