Anti-FAK (Ab-576 / 577) Antibody

Raised in rabbit and affinity-purified by epitope-specific peptide chromatography, this polyclonal reagent from Antibodies.com targets Focal Adhesion Kinase (FAK) at residues surrounding tyrosine 576/577, detecting endogenous levels of total FAK protein across human, mouse, and rat samples. The unconjugated antibody is supplied as a 50 µl liquid at a concentration of 1.0 mg/mL, formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide, and 50% glycerol, and is validated for Western blot and immunohistochemistry applications. The immunogen corresponds to the synthetic peptide sequence around aa. 574–578 / 575–579 (T-Y-Y-K-A) of human FAK (PTK2), making the reagent well suited for researchers investigating focal adhesion signalling, integrin-mediated pathways, and cytoskeletal regulation in cancer, developmental, and cell-biology studies. The product is shipped on wet ice at 4 °C and should be aliquoted upon arrival and stored at −20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Recognised synonyms include FAK1, FADK 1, p125FAK, pp125FAK, FRNK, PPP1R71, and Protein-tyrosine kinase 2, and the antibody is intended for research use only.