Anti-FAH Antibody

This rabbit polyclonal antibody from Antibodies.com specifically targets fumarylacetoacetate hydrolase (FAH), the terminal enzyme in the tyrosine catabolism pathway whose deficiency causes hereditary tyrosinemia type I. The unconjugated IgG reagent is supplied as 50 µl of polyclonal antiserum raised in rabbit, intended for Western blot detection of endogenous FAH protein in human, mouse, and rat samples. Investigators studying hepatic metabolism, inborn errors of tyrosine catabolism, and related liver disease models use this reagent to probe FAH expression in lysates prepared from the listed reactive species. Because the antibody is unconjugated, it pairs with any HRP- or fluorophore-conjugated secondary antibody of choice, giving flexibility for chemiluminescent or fluorescent Western blot workflows. The polyclonal format provides recognition of multiple epitopes on FAH, which can be advantageous when probing denatured target on membrane after SDS-PAGE transfer.