Anti-FADD Antibody

FADD (Fas-Associated Death Domain) is a key adaptor protein that links death receptors such as Fas/CD95 to caspase-8 during extrinsic apoptosis signaling. This Rabbit polyclonal antibody from Antibodies.com is raised against human FADD and is supplied as 100 µl of unconjugated reagent in a single vial. It is validated for western blot and immunohistochemistry workflows, detecting endogenous FADD in human samples to support programmed cell death, immune regulation, and tumor biology research.

The polyclonal format recognizes multiple epitopes on the target, helpful when probing post-translational modifications or low-abundance expression. Researchers apply this reagent to investigate TRAIL- and Fas-driven apoptosis pathways, DISC (death-inducing signaling complex) assembly, and cross-talk with autophagy and necroptosis.

Storage temperature should be kept low with refrigeration; aliquot to limit freeze-thaw cycles and preserve activity across blots and tissue sections.