Anti-Factor XI Antibody

Targeting human Factor XI - the plasma serine protease zymogen that initiates the intrinsic arm of the coagulation cascade - this rabbit polyclonal antibody is supplied by Antibodies.com as a 100 µl liquid aliquot. Factor XI is studied in hemostasis and contact-activation research, and is also clinically relevant to venous thromboembolism risk and to the bleeding disorder hemophilia C (Rosenthal syndrome) caused by heritable FXI deficiency.

Unconjugated and validated by the supplier for Western blot and immunohistochemistry on human samples, the reagent can be paired with a standard anti-rabbit secondary antibody for chromogenic, fluorescent, or chemiluminescent detection. The 100 µl volume is sized to support multiple immunoblots and a series of tissue sections without requiring a large-scale antibody purchase.

Investigators studying contact pathway-driven thrombin generation, hepatic synthesis of coagulation factors, or FXI isoform expression in disease tissue can use the antibody to evaluate protein expression, processing, and cellular localization. The unconjugated format also allows laboratories to conjugate the reagent to a label of their choice, if desired.

Distributed by Antibodies.com.