Anti-F-box only protein 2 Antibody

This polyclonal reagent from Antibodies.com targets F-box only protein 2, a substrate-recognition subunit of the SCF (SKP1-CUL1-F-box) E3 ubiquitin ligase complex.

Antibody specifications:

• Host: Rabbit
• Clonality: Polyclonal
• Conjugate: Unconjugated
• Reactivity: Human
• Size: 100 µl
• Applications: Western Blot, immunohistochemistry

FBXO2 (also called FBG1 or Fbs1) recognizes glycoproteins bearing high-mannose N-linked glycans and has been studied in relation to amyloid precursor protein processing, including regulation of BACE1 levels. The reagent is supplied as a liquid vial for short-term use and supports detection of endogenous FBXO2 in cell and tissue lysates.

The polyclonal format provides recognition of multiple epitopes on the target, which researchers exploit when characterizing SCF-mediated ubiquitination pathways and proteasomal degradation in neurodegeneration studies.