Anti-EZR (phospho Y353) Antibody

This rabbit polyclonal IgG antibody from Antibodies.com is raised against ezrin (EZR) phosphorylated at tyrosine 353, a regulatory residue whose modification drives the conformational activation that links the actin cytoskeleton to the plasma membrane.

Provided as 200 µl of unconjugated reagent in a vial format, the antibody is validated for Western blot and immunohistochemistry on human and mouse samples, supporting research into cytoskeletal remodeling, cell migration, and growth factor signaling where Y353 phosphorylation has been mapped.

The polyclonal host response yields recognition of multiple epitopes surrounding the phospho-Y353 site, useful when monitoring dynamic changes in ezrin activation state across experimental conditions, including studies of epithelial morphogenesis, tumor cell motility, and receptor tyrosine kinase signaling cascades that converge on ERM-family proteins.

Store refrigerated and protect from light to preserve phospho-specific reactivity across repeated use; the unconjugated format allows flexible pairing with secondary reagents of choice.